Carter and Sadie Kane discover they come from a family of ancient Egyptian magicians. After an explosion at the British Museum, their father disappears and the god Set is accidentally released. The siblings soon learn they are connected to the gods Horus and Isis.
Hunted by a secret magical organization called the House of Life, they must quickly learn to control their powers in order to save their father and stop Set from causing chaos. Along their journey, they face mythological creatures and uncover a hidden war between order and chaos.